CMap Candidate Details

Structure:
CMap ID: C34210
Pert ID: BRD-M86331534
Compound Name: pyrvinium-pamoate
Targets: AR
MoA: Akt inhibitor; Androgen receptor antagonist
SMILES: CN(C)c1ccc2[n+](C)c(CCc3cc(C)n(c3C)-c3ccccc3)ccc2c1
InchiKey: JSZNAPGSRFTCQR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9043 BRD-M86331534 A375 10 uM 6 h -0.25 -1.06 0.25 -0.48 -1.6 15.65
9132 BRD-M86331534 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9559 BRD-M86331534 AGS 10 uM 6 h 0.16 0.67 0.0 -0.42 -1.41 2.02
9866 BRD-M86331534 H1299 10 uM 6 h 0.24 1.02 0.12 -0.4 -1.33 1.84
10102 BRD-M86331534 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.25
10194 BRD-M86331534 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
10642 BRD-M86331534 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10890 BRD-M86331534 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11092 BRD-M86331534 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.67
11630 BRD-M86331534 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12183 BRD-M86331534 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12637 BRD-M86331534 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12916 BRD-M86331534 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13039 BRD-M86331534 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13408 BRD-M86331534 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
88522 BRD-M86331534 VCAP 2.22 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
96043 BRD-M86331534 PHH 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97559 BRD-M86331534 MCF??7.00 10 uM 6 h 0.25 1.06 0.18 -0.42 -1.41 2.02
97616 BRD-M86331534 NKDBA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).