CMap Candidate Details

Structure:
CMap ID: C34250
Pert ID: BRD-U07805514
Compound Name: saracatinib
Targets: ABL1; SRC
MoA: Src inhibitor
SMILES: CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
InchiKey: OUKYUETWWIPKQR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
94402 BRD-U07805514 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94434 BRD-U07805514 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94468 BRD-U07805514 ASC 3.33 uM 24 h 0.18 0.76 0.0 0.0 0.0 0.0
94528 BRD-U07805514 CD34 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94582 BRD-U07805514 HCC515 1.11 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.1
94622 BRD-U07805514 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94672 BRD-U07805514 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94721 BRD-U07805514 HME1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94777 BRD-U07805514 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94817 BRD-U07805514 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94869 BRD-U07805514 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.3 -0.99 0.51
94921 BRD-U07805514 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94964 BRD-U07805514 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.2 -0.67 0.02
94996 BRD-U07805514 NEU 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95067 BRD-U07805514 NPC 1.11 uM 24 h -0.21 -0.88 0.03 0.35 1.23 1.19
95103 BRD-U07805514 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95141 BRD-U07805514 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95227 BRD-U07805514 SKL 3.33 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
95254 BRD-U07805514 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.26
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).