CMap Candidate Details

Structure:
CMap ID: C34331
Pert ID: BRD-U94846492
Compound Name: quinine
Targets: KCNN4
MoA: Hemozoin biocrystallization inhibitor
SMILES: COc1ccc2nccc([C@@H](O)[C@H]3C[C@@H]4CC[N@]3C[C@@H]4C=C)c2c1
InchiKey: LOUPRKONTZGTKE-AFHBHXEDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9016 BRD-U94846492 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9134 BRD-U94846492 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9561 BRD-U94846492 AGS 10 uM 6 h 0.0 0.0 0.0 0.36 1.27 1.34
9868 BRD-U94846492 H1299 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.79 0.11
10103 BRD-U94846492 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.66
10308 BRD-U94846492 HCC515 10 uM 6 h -0.29 -1.19 0.55 0.3 1.07 0.63
10643 BRD-U94846492 HCT116 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.62
10891 BRD-U94846492 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11087 BRD-U94846492 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11186 BRD-U94846492 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11632 BRD-U94846492 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.68
12185 BRD-U94846492 NCIH596 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
12502 BRD-U94846492 PC3 10 uM 24 h -0.26 -1.07 0.27 0.0 0.0 0.0
13716 BRD-U94846492 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).