CMap Candidate Details

Structure:
CMap ID: C00349
Pert ID: BRD-A13946108
Compound Name: sulindac
Targets: AKR1B1; PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: CC1=C(CC(O)=O)c2cc(F)ccc2C1=C/c1ccc(cc1)S(C)=O
InchiKey: MLKXDPUZXIRXEP-MFOYZWKCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49754 BRD-A13946108 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
49932 BRD-A13946108 A549 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.18 1.14
50096 BRD-A13946108 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50281 BRD-A13946108 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50450 BRD-A13946108 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50626 BRD-A13946108 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
50881 BRD-A13946108 PC3 10 uM 6 h 0.0 0.0 0.0 -0.44 -1.48 15.35
51089 BRD-A13946108 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98969 BRD-A13946108 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99115 BRD-A13946108 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).