CMap Candidate Details

Structure:
CMap ID: C03507
Pert ID: BRD-K03440695
Compound Name: boldine
Targets: --
MoA: --
SMILES: COc1cc-2c(C[C@@H]3N(C)CCc4cc(O)c(OC)c2c34)cc1O
InchiKey: LZJRNLRASBVRRX-ZDUSSCGKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4184 BRD-K03440695 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.81
4342 BRD-K03440695 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.4 2.02
4636 BRD-K03440695 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4877 BRD-K03440695 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44281 BRD-K03440695 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44508 BRD-K03440695 A549 10 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
44818 BRD-K03440695 ASC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.91
45132 BRD-K03440695 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45401 BRD-K03440695 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45635 BRD-K03440695 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
45933 BRD-K03440695 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46252 BRD-K03440695 PHH 10 uM 24 h -0.2 -0.82 0.0 -0.3 -1.02 0.6
46568 BRD-K03440695 SKB 10 uM 24 h 0.28 1.17 0.37 -0.22 -0.74 0.05
99980 BRD-K03440695 U2OS 6.66 uM 6 h 0.22 0.9 0.03 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).