CMap Candidate Details

Structure:
CMap ID: C03561
Pert ID: BRD-K03601870
Compound Name: ixabepilone
Targets: TUBB3
MoA: Microtubule stabilizing agent
SMILES: C[C@H]1CCC[C@@]2(C)O[C@H]2C[C@H](NC(=O)C[C@H](O)C(C)(C)C(=O)[C@H](C)[C@H]1O)C(C)=Cc1csc(C)n1
InchiKey: FABUFPQFXZVHFB-PVYNADRNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122560 BRD-K03601870 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122591 BRD-K03601870 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122615 BRD-K03601870 HEK293 3.33 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
122667 BRD-K03601870 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122694 BRD-K03601870 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130855 BRD-K03601870 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130947 BRD-K03601870 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131015 BRD-K03601870 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131069 BRD-K03601870 MCF??7.00 0.25 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
131101 BRD-K03601870 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.07
131135 BRD-K03601870 PC3 0.74 uM 24 h -0.27 -1.14 0.43 0.0 0.0 0.0
131164 BRD-K03601870 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).