CMap Candidate Details

Structure:
CMap ID: C00361
Pert ID: BRD-A14262390
Compound Name: guanadrel
Targets: SLC6A2
MoA: Adrenergic inhibitor
SMILES: NC(=N)NCC1COC2(CCCCC2)O1
InchiKey: HPBNRIOWIXYZFK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122258 BRD-A14262390 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122299 BRD-A14262390 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122319 BRD-A14262390 HEK293 0.37 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.21
122365 BRD-A14262390 MCF10A 3.33 uM 24 h -0.18 -0.74 0.0 0.0 0.0 0.0
122392 BRD-A14262390 MCF??7.00 0.04 uM 24 h -0.23 -0.97 0.1 -0.29 -0.97 0.45
122442 BRD-A14262390 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122481 BRD-A14262390 THP1 0.04 uM 24 h -0.26 -1.07 0.27 0.0 0.0 0.0
122519 BRD-A14262390 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130561 BRD-A14262390 A549 0.25 uM 24 h -0.24 -1.02 0.18 0.0 0.0 0.0
130673 BRD-A14262390 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130713 BRD-A14262390 HT29 0.01 uM 24 h 0.24 1.0 0.1 -0.24 -0.81 0.13
130787 BRD-A14262390 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.71
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).