CMap Candidate Details

Structure:
CMap ID: C03624
Pert ID: BRD-K03816923
Compound Name: rottlerin
Targets: --
MoA: --
SMILES: CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c(C(=O)/C=C/c3ccccc3)c4OC(C)(C)C=Cc4c2O)c1O
InchiKey: DEZFNHCVIZBHBI-ZHACJKMWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1724 BRD-K03816923 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9339 BRD-K03816923 AGS 10 uM 6 h 0.0 0.0 0.0 0.39 1.38 2.16
9645 BRD-K03816923 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10196 BRD-K03816923 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.03 0.62
10443 BRD-K03816923 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11201 BRD-K03816923 MCF??7.00 10 uM 24 h 0.14 0.58 0.0 -0.35 -1.18 1.14
11395 BRD-K03816923 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11696 BRD-K03816923 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11966 BRD-K03816923 NCIH596 10 uM 6 h 0.26 1.08 0.2 0.0 0.0 0.0
12250 BRD-K03816923 NOMO1 10 uM 6 h 0.2 0.84 0.0 0.28 1.0 0.43
12711 BRD-K03816923 SW480 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.41 2.02
13042 BRD-K03816923 THP1 10 uM 6 h 0.0 0.0 0.0 0.26 0.9 0.22
13192 BRD-K03816923 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13441 BRD-K03816923 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
16199 BRD-K03816923 A375 10 uM 24 h 0.27 1.13 0.28 0.0 0.0 0.0
18224 BRD-K03816923 PC3 10 uM 24 h 0.32 1.33 0.84 -0.28 -0.95 0.4
44821 BRD-K03816923 ASC 10 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
45135 BRD-K03816923 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45936 BRD-K03816923 NPC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
46255 BRD-K03816923 PHH 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.28
46571 BRD-K03816923 SKB 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
96105 BRD-K03816923 A549 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.49 15.35
98992 BRD-K03816923 NEU 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
122919 BRD-K03816923 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123044 BRD-K03816923 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123134 BRD-K03816923 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131317 BRD-K03816923 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.24 0.87 0.17
131330 BRD-K03816923 HT29 2.22 uM 24 h 0.22 0.91 0.04 0.0 0.0 0.0
131381 BRD-K03816923 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131416 BRD-K03816923 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
131514 BRD-K03816923 YAPC 2.22 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).