CMap Candidate Details

Structure:
CMap ID: C03630
Pert ID: BRD-K03842655
Compound Name: penitrem-a
Targets: KCNMA1
MoA: Potassium channel blocker
SMILES: CC(=C)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@@H](CC[C@@]3(O)[C@@]52O[C@@H]5[C@H]1O)[C@@H]6OC(C)(C)[C@H]7C[C@@H]8C(=C)Cc9c(Cl)cc%10[nH]c4c6c%10c9[C@@]87O
InchiKey: JDUWHZOLEDOQSR-JKPSMKLGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5176 BRD-K03842655 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5294 BRD-K03842655 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
5752 BRD-K03842655 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6513 BRD-K03842655 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44822 BRD-K03842655 ASC 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
45136 BRD-K03842655 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.36 2.02
45404 BRD-K03842655 HT29 10 uM 6 h 0.0 0.0 0.0 0.33 1.15 0.9
45762 BRD-K03842655 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
45937 BRD-K03842655 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46256 BRD-K03842655 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46572 BRD-K03842655 SKB 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.04
99985 BRD-K03842655 U2OS 8 uM 6 h 0.19 0.78 0.0 0.0 0.0 0.0
120010 BRD-K03842655 A549 2.22 uM 24 h 0.0 0.0 0.0 0.22 0.76 0.05
120077 BRD-K03842655 HELA 0.01 uM 3 h 0.26 1.07 0.2 0.0 0.0 0.0
128853 BRD-K03842655 PC3 0.002 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128886 BRD-K03842655 YAPC 0.002 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).