CMap Candidate Details

Structure:
CMap ID: C00364
Pert ID: BRD-A14395271
Compound Name: mesoridazine
Targets: DRD2; HTR2A
MoA: Dopamine receptor antagonist
SMILES: CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O
InchiKey: SLVMESMUVMCQIY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4276 BRD-A14395271 HCC515 10 uM 24 h -0.33 -1.38 1.08 0.0 0.0 0.0
4836 BRD-A14395271 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
9271 BRD-A14395271 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9574 BRD-A14395271 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9914 BRD-A14395271 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
10653 BRD-A14395271 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.65
10896 BRD-A14395271 HT29 10 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
11169 BRD-A14395271 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11323 BRD-A14395271 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11642 BRD-A14395271 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11893 BRD-A14395271 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.06
12191 BRD-A14395271 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.34
12482 BRD-A14395271 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12650 BRD-A14395271 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44232 BRD-A14395271 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44475 BRD-A14395271 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44746 BRD-A14395271 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45865 BRD-A14395271 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46178 BRD-A14395271 PHH 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
46494 BRD-A14395271 SKB 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
91344 BRD-A14395271 HUH7 8 uM 72 h 0.0 0.0 0.0 0.28 1.0 0.42
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).