CMap Candidate Details

Structure:
CMap ID: C03671
Pert ID: BRD-K03981224
Compound Name: ethisterone
Targets: --
MoA: --
SMILES: C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@]2(O)C#C
InchiKey: CHNXZKVNWQUJIB-CEGNMAFCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4043 BRD-K03981224 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
4536 BRD-K03981224 HCC515 10 uM 6 h 0.27 1.13 0.29 -0.36 -1.2 1.16
4638 BRD-K03981224 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5022 BRD-K03981224 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44283 BRD-K03981224 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44510 BRD-K03981224 A549 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
44823 BRD-K03981224 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45137 BRD-K03981224 HEPG2 10 uM 6 h 0.2 0.84 0.0 0.24 0.85 0.15
45405 BRD-K03981224 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45637 BRD-K03981224 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
45938 BRD-K03981224 NPC 10 uM 24 h 0.25 1.04 0.15 -0.25 -0.84 0.18
46257 BRD-K03981224 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46573 BRD-K03981224 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91276 BRD-K03981224 HUH7 10 uM 72 h 0.32 1.33 0.85 -0.24 -0.81 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).