CMap Candidate Details

Structure:
CMap ID: C00368
Pert ID: BRD-A14566392
Compound Name: scopolamine
Targets: CHRM1; CHRM2; CHRM3; CHRM4
MoA: Acetylcholine receptor antagonist
SMILES: CN1C2CC(CC1C3OC32)OC(=O)C(CO)c4ccccc4
InchiKey: STECJAGHUSJQJN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1680 BRD-A14566392 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1809 BRD-A14566392 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2318 BRD-A14566392 PC3 10 uM 6 h 0.28 1.17 0.38 0.0 0.0 0.0
2620 BRD-A14566392 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41646 BRD-A14566392 A375 10 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
41997 BRD-A14566392 A549 10 uM 6 h -0.24 -1.0 0.14 0.0 0.0 0.0
42176 BRD-A14566392 ASC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
42521 BRD-A14566392 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.72
42831 BRD-A14566392 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43111 BRD-A14566392 MCF??7.00 10 uM 24 h -0.24 -1.0 0.15 0.29 1.02 0.48
43377 BRD-A14566392 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
43693 BRD-A14566392 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).