CMap Candidate Details

Structure:
CMap ID: C03687
Pert ID: BRD-K04046242
Compound Name: equilin
Targets: HSD17B1
MoA: Estrogen receptor agonist
SMILES: C[C@@]12CC[C@H]3C(=CCc4cc(O)ccc34)[C@@H]2CCC1=O
InchiKey: WKRLQDKEXYKHJB-HFTRVMKXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5023 BRD-K04046242 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.45
44660 BRD-K04046242 A549 10 uM 6 h 0.0 0.0 0.0 0.32 1.13 0.84
44824 BRD-K04046242 ASC 10 uM 24 h 0.0 0.0 0.0 0.16 0.57 0.0
45764 BRD-K04046242 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.7 0.03
45940 BRD-K04046242 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46259 BRD-K04046242 PHH 10 uM 24 h -0.33 -1.38 1.08 -0.3 -1.02 0.6
46575 BRD-K04046242 SKB 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.89
99986 BRD-K04046242 U2OS 8 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119172 BRD-K04046242 A375 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119230 BRD-K04046242 HA1E 0.12 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
119258 BRD-K04046242 HCC515 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
119289 BRD-K04046242 HEPG2 0.37 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.98
119316 BRD-K04046242 HT29 0.12 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
119367 BRD-K04046242 PC3 1.11 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).