CMap Candidate Details

Structure:
CMap ID: C00369
Pert ID: BRD-A14574269
Compound Name: UB-165
Targets: CHRNA3; CHRNA4; CHRNB2
MoA: Acetylcholine receptor agonist
SMILES: Clc1ccc(cn1)C1=CCCC2CCC1N2
InchiKey: TVSNVPGPFGAKPT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1681 BRD-A14574269 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1810 BRD-A14574269 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2259 BRD-A14574269 PC3 10 uM 24 h 0.0 0.0 0.0 0.4 1.41 2.19
2588 BRD-A14574269 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41647 BRD-A14574269 A375 10 uM 6 h 0.0 0.0 0.0 0.22 0.79 0.07
41871 BRD-A14574269 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42177 BRD-A14574269 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42522 BRD-A14574269 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42832 BRD-A14574269 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43112 BRD-A14574269 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43378 BRD-A14574269 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43694 BRD-A14574269 PHH 10 uM 24 h -0.2 -0.83 0.0 0.32 1.13 0.84
43992 BRD-A14574269 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).