CMap Candidate Details

Structure:
CMap ID: C03704
Pert ID: BRD-K04111260
Compound Name: raclopride
Targets: DRD2; DRD3
MoA: Dopamine receptor antagonist
SMILES: CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC
InchiKey: WAOQONBSWFLFPE-VIFPVBQESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3130 BRD-K04111260 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3936 BRD-K04111260 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.4
39422 BRD-K04111260 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39619 BRD-K04111260 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39939 BRD-K04111260 HEPG2 10 uM 6 h -0.19 -0.8 0.0 0.0 0.0 0.0
40743 BRD-K04111260 NEU 10 uM 24 h -0.27 -1.11 0.37 0.0 0.0 0.0
41043 BRD-K04111260 NPC 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.08
41370 BRD-K04111260 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51582 BRD-K04111260 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51796 BRD-K04111260 PC3 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
90954 BRD-K04111260 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99987 BRD-K04111260 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
122616 BRD-K04111260 HEK293 0.04 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
122695 BRD-K04111260 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130856 BRD-K04111260 A375 2.22 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
130897 BRD-K04111260 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130948 BRD-K04111260 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
130986 BRD-K04111260 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
131016 BRD-K04111260 HUVEC 0.01 uM 24 h -0.25 -1.04 0.21 0.0 0.0 0.0
131102 BRD-K04111260 MDAMB231 0.08 uM 24 h 0.23 0.96 0.07 -0.42 -1.4 2.02
131165 BRD-K04111260 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).