CMap Candidate Details

Structure:
CMap ID: C03715
Pert ID: BRD-K04146668
Compound Name: GW-441756
Targets: NTRK1
MoA: Growth factor receptor inhibitor
SMILES: Cn1cc(C=C2C(=O)Nc3cccnc23)c4ccccc14
InchiKey: NXNQLECPAXXYTR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2828 BRD-K04146668 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.21
3328 BRD-K04146668 HCC515 10 uM 6 h 0.24 1.02 0.13 0.31 1.09 0.67
3460 BRD-K04146668 PC3 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
3713 BRD-K04146668 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
39085 BRD-K04146668 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39423 BRD-K04146668 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39620 BRD-K04146668 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39940 BRD-K04146668 HEPG2 10 uM 6 h 0.25 1.03 0.13 0.25 0.87 0.17
40220 BRD-K04146668 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40450 BRD-K04146668 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41044 BRD-K04146668 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41371 BRD-K04146668 SKB 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).