CMap Candidate Details

Structure:
CMap ID: C03730
Pert ID: BRD-K04196797
Compound Name: oxcarbazepine
Targets: SCN1A; SCN3A; SCN5A
MoA: Sodium channel blocker
SMILES: NC(=O)N1c2ccccc2CC(=O)c2ccccc12
InchiKey: CTRLABGOLIVAIY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24650 BRD-K04196797 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24745 BRD-K04196797 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24866 BRD-K04196797 HT29 10 uM 6 h -0.27 -1.11 0.36 0.0 0.0 0.0
25002 BRD-K04196797 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25320 BRD-K04196797 VCAP 10 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.14
51913 BRD-K04196797 PC3 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.88
91296 BRD-K04196797 HUH7 12.5 uM 72 h 0.0 0.0 0.0 -0.3 -1.0 0.55
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).