CMap Candidate Details

Structure:
CMap ID: C03732
Pert ID: BRD-K04210847
Compound Name: tamoxifen
Targets: ESR1; ESR2
MoA: Estrogen receptor antagonist; Selective estrogen receptor modulator
SMILES: CC/C(=C(c1ccc(O)cc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3
InchiKey: TXUZVZSFRXZGTL-QPLCGJKRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6863 BRD-K04210847 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7133 BRD-K04210847 A549 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.44
7290 BRD-K04210847 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7617 BRD-K04210847 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7829 BRD-K04210847 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8074 BRD-K04210847 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8344 BRD-K04210847 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8797 BRD-K04210847 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).