CMap Candidate Details

Structure:
CMap ID: C00374
Pert ID: BRD-A14798026
Compound Name: mestranol
Targets: ESR1
MoA: Estrogen receptor agonist
SMILES: COc1ccc2C3CC[C@@]4(C)C(CC[C@@]4(O)C#C)C3CCc2c1
InchiKey: IMSSROKUHAOUJS-VYJKVFMHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3088 BRD-A14798026 HCC515 10 uM 24 h -0.25 -1.03 0.19 0.23 0.81 0.09
3665 BRD-A14798026 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44747 BRD-A14798026 ASC 10 uM 24 h -0.19 -0.79 0.0 -0.31 -1.05 0.71
45068 BRD-A14798026 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45866 BRD-A14798026 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
46179 BRD-A14798026 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46495 BRD-A14798026 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122261 BRD-A14798026 A375 0.125 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
122332 BRD-A14798026 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122394 BRD-A14798026 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122443 BRD-A14798026 PC3 0.04 uM 24 h 0.23 0.94 0.06 0.33 1.16 0.9
122484 BRD-A14798026 THP1 10 uM 24 h -0.23 -0.94 0.08 0.26 0.9 0.23
122520 BRD-A14798026 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130564 BRD-A14798026 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130597 BRD-A14798026 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130631 BRD-A14798026 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130716 BRD-A14798026 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130745 BRD-A14798026 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
130790 BRD-A14798026 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).