CMap Candidate Details

Structure:
CMap ID: C03787
Pert ID: BRD-K04389336
Compound Name: labetalol
Targets: ADRA1D; ADRA1A; ADRB1; ADRB2
MoA: Adrenergic receptor antagonist
SMILES: C[C@H](CCc1ccccc1)NC[C@H](O)c1ccc(O)c(c1)C(N)=O
InchiKey: SGUAFYQXFOLMHL-ACJLOTCBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49799 BRD-K04389336 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50140 BRD-K04389336 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
50328 BRD-K04389336 HCC515 10 uM 6 h 0.18 0.75 0.0 0.0 0.0 0.0
50494 BRD-K04389336 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50731 BRD-K04389336 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50902 BRD-K04389336 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51119 BRD-K04389336 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).