CMap Candidate Details

Structure:
CMap ID: C03797
Pert ID: BRD-K04414442
Compound Name: SB-222200
Targets: TACR3
MoA: Tachykinin antagonist
SMILES: CC[C@H](NC(=O)c1c(C)c(nc2ccccc12)-c1ccccc1)c1ccccc1
InchiKey: MQNYRKWJSMQECI-QFIPXVFZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1725 BRD-K04414442 HA1E 10 uM 6 h 0.31 1.28 0.6 0.0 0.0 0.0
2068 BRD-K04414442 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2207 BRD-K04414442 PC3 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
2696 BRD-K04414442 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41704 BRD-K04414442 A375 10 uM 6 h 0.0 0.0 0.0 0.22 0.77 0.06
41899 BRD-K04414442 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42264 BRD-K04414442 ASC 10 uM 24 h 0.25 1.05 0.16 0.0 0.0 0.0
42600 BRD-K04414442 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42904 BRD-K04414442 HT29 10 uM 6 h 0.0 0.0 0.0 0.4 1.4 2.18
43281 BRD-K04414442 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43459 BRD-K04414442 NPC 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.43
43766 BRD-K04414442 PHH 10 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).