CMap Candidate Details

Structure:
CMap ID: C00380
Pert ID: BRD-A14966924
Compound Name: alaproclate
Targets: SLC6A4
MoA: Serotonin receptor antagonist
SMILES: CC(N)C(=O)OC(C)(C)Cc1ccc(Cl)cc1
InchiKey: FZSPJBYOKQPKCD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5498 BRD-A14966924 HCC515 10 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
5825 BRD-A14966924 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6381 BRD-A14966924 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
37445 BRD-A14966924 ASC 10 uM 24 h -0.31 -1.29 0.79 -0.38 -1.27 1.43
38297 BRD-A14966924 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
38821 BRD-A14966924 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122267 BRD-A14966924 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122303 BRD-A14966924 HA1E 3.33 uM 24 h -0.25 -1.05 0.22 0.0 0.0 0.0
122335 BRD-A14966924 HELA 0.04 uM 24 h -0.2 -0.84 0.01 0.0 0.0 0.0
122446 BRD-A14966924 PC3 10 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
122490 BRD-A14966924 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122524 BRD-A14966924 YAPC 1.11 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
130568 BRD-A14966924 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130635 BRD-A14966924 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.11
130720 BRD-A14966924 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
130746 BRD-A14966924 MCF10A 0.74 uM 24 h -0.31 -1.28 0.77 -0.2 -0.68 0.02
130766 BRD-A14966924 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
130793 BRD-A14966924 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).