CMap Candidate Details

Structure:
CMap ID: C03813
Pert ID: BRD-K04466929
Compound Name: Merck60
Targets: HDAC1; HDAC2
MoA: HDAC inhibitor
SMILES: CC(=O)Nc1ccc(cc1)C(=O)Nc2cc(ccc2N)c3cccs3
InchiKey: ABZSPJVXTTUFAA-UHFFFAOYSA-N
Compound Aliases: MERCK-60

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49448 BRD-K04466929 VCAP 10 uM 24 h 0.3 1.24 0.51 0.21 0.73 0.03
95972 BRD-K04466929 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96190 BRD-K04466929 A549 10 uM 24 h -0.17 -0.7 0.0 -0.35 -1.18 1.15
96254 BRD-K04466929 U2OS 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98008 BRD-K04466929 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98041 BRD-K04466929 MCF??7.00 10 uM 24 h -0.32 -1.33 0.91 -0.32 -1.09 0.84
98096 BRD-K04466929 P1A82 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.09
119387 BRD-K04466929 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119485 BRD-K04466929 HCC515 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119522 BRD-K04466929 HEPG2 0.12 uM 24 h -0.24 -1.01 0.17 0.0 0.0 0.0
119556 BRD-K04466929 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119619 BRD-K04466929 PC3 0.04 uM 24 h -0.17 -0.71 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).