CMap Candidate Details

Structure:
CMap ID: C03834
Pert ID: BRD-K04546108
Compound Name: BRD-K04546108
Targets: --
MoA: --
SMILES: O=C/1Nc2ccc(cc2C1=Cc3ccc[nH]3)c4cccnc4
InchiKey: IQNTXIMXKCURDC-YBEGLDIGSA-N
Compound Aliases: JAK3-inhibitor-VI

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1726 BRD-K04546108 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2069 BRD-K04546108 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2302 BRD-K04546108 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2791 BRD-K04546108 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41705 BRD-K04546108 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42044 BRD-K04546108 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42265 BRD-K04546108 ASC 10 uM 24 h 0.0 0.0 0.0 0.39 1.39 2.17
42601 BRD-K04546108 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42905 BRD-K04546108 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43148 BRD-K04546108 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43460 BRD-K04546108 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43767 BRD-K04546108 PHH 10 uM 24 h 0.27 1.13 0.3 0.0 0.0 0.0
44047 BRD-K04546108 SKB 10 uM 24 h 0.22 0.91 0.03 -0.19 -0.65 0.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).