CMap Candidate Details

Structure:
CMap ID: C00384
Pert ID: BRD-A15010982
Compound Name: HU-211
Targets: CNR1; CNR2; GRIN1
MoA: Glutamate receptor antagonist
SMILES: CCCCCCC(C)(C)c1cc(O)c2[C@H]3CC(CO)=CCC3C(C)(C)Oc2c1
InchiKey: SSQJFGMEZBFMNV-XJDOXCRVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25774 BRD-A15010982 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25872 BRD-A15010982 A549 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
26191 BRD-A15010982 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26537 BRD-A15010982 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26852 BRD-A15010982 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.43 15.35
27155 BRD-A15010982 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27648 BRD-A15010982 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.45 -1.51 15.35
27785 BRD-A15010982 NEU 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
28094 BRD-A15010982 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28560 BRD-A15010982 PC3 10 uM 6 h 0.17 0.71 0.0 -0.32 -1.08 0.81
28732 BRD-A15010982 PHH 10 uM 24 h -0.21 -0.88 0.03 -0.31 -1.06 0.73
29043 BRD-A15010982 SKB 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.25
29383 BRD-A15010982 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).