CMap Candidate Details

Structure:
CMap ID: C00385
Pert ID: BRD-A15034104
Compound Name: bergenin
Targets: IL1B; TNF
MoA: Interleukin inhibitor
SMILES: COc1c(O)cc2C(=O)OC3C(O)C(O)C(CO)OC3c2c1O
InchiKey: YWJXCIXBAKGUKZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6827 BRD-A15034104 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7056 BRD-A15034104 A549 10 uM 6 h 0.19 0.77 0.0 0.25 0.9 0.22
7208 BRD-A15034104 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7509 BRD-A15034104 HCC515 10 uM 6 h 0.31 1.3 0.73 0.28 0.98 0.37
7746 BRD-A15034104 HT29 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.29
8038 BRD-A15034104 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
8428 BRD-A15034104 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8550 BRD-A15034104 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).