CMap Candidate Details

Structure:
CMap ID: C00386
Pert ID: BRD-A15070535
Compound Name: bucladesine
Targets: PRKACA
MoA: CAMP stimulant; Adenosine receptor agonist
SMILES: CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4OP(=O)(O)OC[C@H]4[C@H]3OC(=O)CCC
InchiKey: ZKSUYDZTGVUZGX-VBJMPTANSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6620 BRD-A15070535 A375 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.92
6916 BRD-A15070535 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7209 BRD-A15070535 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7936 BRD-A15070535 HT29 10 uM 6 h 0.21 0.87 0.01 0.31 1.1 0.69
8144 BRD-A15070535 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
8293 BRD-A15070535 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8551 BRD-A15070535 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).