CMap Candidate Details

Structure:
CMap ID: C03885
Pert ID: BRD-K04701033
Compound Name: VE-822
Targets: ATR
MoA: ATR kinase inhibitor
SMILES: CNCc1ccc(cc1)-c1cc(on1)-c1nc(cnc1N)-c1ccc(cc1)S(=O)(=O)C(C)C
InchiKey: JZCWLJDSIRUGIN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95822 BRD-K04701033 A375 0.12 uM 6 h -0.25 -1.05 0.24 0.0 0.0 0.0
95847 BRD-K04701033 NPC 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95880 BRD-K04701033 MCF??7.00 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95902 BRD-K04701033 YAPC 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95950 BRD-K04701033 A549 0.12 uM 6 h 0.17 0.7 0.0 0.0 0.0 0.0
95963 BRD-K04701033 PC3 0.12 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.5
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).