CMap Candidate Details

Structure:
CMap ID: C00391
Pert ID: BRD-A15131297
Compound Name: benazepril
Targets: ACE
MoA: Angiotensin converting enzyme inhibitor
SMILES: CCOC(=O)C(CCc1ccccc1)NC2CCc3ccccc3N(CC(=O)O)C2=O
InchiKey: XPCFTKFZXHTYIP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5388 BRD-A15131297 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.13 0.97
5499 BRD-A15131297 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5826 BRD-A15131297 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6236 BRD-A15131297 PC3 10 uM 6 h 0.0 0.0 0.0 0.41 1.46 2.23
6450 BRD-A15131297 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44233 BRD-A15131297 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44635 BRD-A15131297 A549 10 uM 6 h 0.21 0.86 0.01 0.33 1.16 0.9
44748 BRD-A15131297 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45349 BRD-A15131297 HT29 10 uM 6 h 0.0 0.0 0.0 0.22 0.76 0.05
45734 BRD-A15131297 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.79 0.11
45867 BRD-A15131297 NPC 10 uM 24 h 0.0 0.0 0.0 0.35 1.22 1.19
46180 BRD-A15131297 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46496 BRD-A15131297 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).