CMap Candidate Details

Structure:
CMap ID: C00392
Pert ID: BRD-A15202882
Compound Name: milnacipran
Targets: SLC6A2; SLC6A4
MoA: Serotonin reuptake inhibitor
SMILES: CCN(CC)C(=O)C1(CC1CN)c1ccccc1
InchiKey: GJJFMKBJSRMPLA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122271 BRD-A15202882 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122306 BRD-A15202882 HA1E 10 uM 24 h 0.21 0.88 0.01 -0.36 -1.21 1.24
122324 BRD-A15202882 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122375 BRD-A15202882 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 -0.41 -1.4 2.02
122402 BRD-A15202882 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
122449 BRD-A15202882 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122496 BRD-A15202882 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122528 BRD-A15202882 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.91
130571 BRD-A15202882 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130683 BRD-A15202882 HELA 0.25 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
130726 BRD-A15202882 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130798 BRD-A15202882 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).