CMap Candidate Details

Structure:
CMap ID: C03944
Pert ID: BRD-K04887706
Compound Name: BRD-K04887706
Targets: --
MoA: --
SMILES: O=c1[nH]c2ccccc2n1C3CCN(Cc4ccc(cc4)c5nc6cc7[nH]cnc7cc6nc5c8ccccc8)CC3
InchiKey: BIWGYFZAEWGBAL-UHFFFAOYSA-N
Compound Aliases: AKT-inhibitor-1-2

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9167 BRD-K04887706 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9344 BRD-K04887706 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9650 BRD-K04887706 H1299 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.08
10025 BRD-K04887706 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10112 BRD-K04887706 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10717 BRD-K04887706 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.37 1.32 1.59
11053 BRD-K04887706 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11400 BRD-K04887706 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.63
11970 BRD-K04887706 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
12928 BRD-K04887706 THP1 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
13195 BRD-K04887706 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13571 BRD-K04887706 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91735 BRD-K04887706 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.06
91980 BRD-K04887706 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92010 BRD-K04887706 BT20 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92124 BRD-K04887706 HS578T 0.04 uM 24 h 0.0 0.0 0.0 -0.33 -1.09 0.84
92206 BRD-K04887706 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92248 BRD-K04887706 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92281 BRD-K04887706 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92328 BRD-K04887706 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95442 BRD-K04887706 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
125309 BRD-K04887706 HEK293 10 uM 24 h -0.22 -0.91 0.05 0.32 1.13 0.83
125396 BRD-K04887706 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133418 BRD-K04887706 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.71
133629 BRD-K04887706 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).