CMap Candidate Details

Structure:
CMap ID: C00396
Pert ID: BRD-A15435692
Compound Name: BMY-14802
Targets: HTR1A
MoA: Sigma receptor antagonist
SMILES: OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1
InchiKey: ZXUYYZPJUGQHLQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1811 BRD-A15435692 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2590 BRD-A15435692 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42178 BRD-A15435692 ASC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.77
42523 BRD-A15435692 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43379 BRD-A15435692 NPC 10 uM 24 h -0.33 -1.39 1.14 -0.41 -1.37 2.02
43695 BRD-A15435692 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
122276 BRD-A15435692 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122341 BRD-A15435692 HELA 10 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.28
122429 BRD-A15435692 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122502 BRD-A15435692 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130575 BRD-A15435692 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130606 BRD-A15435692 HA1E 0.03 uM 24 h -0.21 -0.87 0.02 -0.35 -1.17 1.14
130646 BRD-A15435692 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130729 BRD-A15435692 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.19 0.67 0.01
130752 BRD-A15435692 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130770 BRD-A15435692 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130823 BRD-A15435692 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130851 BRD-A15435692 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).