CMap Candidate Details

Structure:
CMap ID: C03963
Pert ID: BRD-K04976539
Compound Name: aminogenistein
Targets: LCK
MoA: Src inhibitor
SMILES: Nc1ccc(cc1)c2cc(=O)c3cc(O)ccc3o2
InchiKey: YBQRUOMICVULNM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1531 BRD-K04976539 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2070 BRD-K04976539 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2363 BRD-K04976539 PC3 10 uM 6 h 0.27 1.12 0.28 0.32 1.14 0.87
2511 BRD-K04976539 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41706 BRD-K04976539 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41900 BRD-K04976539 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42266 BRD-K04976539 ASC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
42602 BRD-K04976539 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42906 BRD-K04976539 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43149 BRD-K04976539 MCF??7.00 10 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
43461 BRD-K04976539 NPC 10 uM 24 h 0.17 0.72 0.0 -0.37 -1.26 1.38
43768 BRD-K04976539 PHH 10 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
99990 BRD-K04976539 U2OS 10 uM 6 h 0.21 0.88 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).