CMap Candidate Details

Structure:
CMap ID: C00040
Pert ID: BRD-A01643550
Compound Name: prednisolone-acetate
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3[C@@H](O)C[C@]12C
InchiKey: LRJOMUJRLNCICJ-AUGMLKDDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5245 BRD-A01643550 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.33 1.84
5485 BRD-A01643550 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
5969 BRD-A01643550 HT29 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.59
6119 BRD-A01643550 PC3 10 uM 24 h 0.0 0.0 0.0 0.37 1.31 1.59
6444 BRD-A01643550 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37033 BRD-A01643550 A375 10 uM 6 h 0.23 0.97 0.08 -0.24 -0.8 0.12
37207 BRD-A01643550 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
37425 BRD-A01643550 ASC 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
37778 BRD-A01643550 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38122 BRD-A01643550 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38279 BRD-A01643550 NPC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.02
38591 BRD-A01643550 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38808 BRD-A01643550 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).