CMap Candidate Details

Structure:
CMap ID: C04027
Pert ID: BRD-K05181463
Compound Name: L-741626
Targets: DRD2
MoA: Dopamine receptor antagonist
SMILES: OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c4ccc(Cl)cc4
InchiKey: LLBLNMUONVVVPG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2978 BRD-K05181463 HA1E 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.5
3131 BRD-K05181463 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3461 BRD-K05181463 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3714 BRD-K05181463 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39086 BRD-K05181463 A375 10 uM 6 h 0.31 1.27 0.59 -0.25 -0.85 0.2
39294 BRD-K05181463 A549 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
39941 BRD-K05181463 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40221 BRD-K05181463 HT29 10 uM 6 h -0.21 -0.86 0.02 0.0 0.0 0.0
40586 BRD-K05181463 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.33 1.16 0.9
40744 BRD-K05181463 NEU 10 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
41045 BRD-K05181463 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41372 BRD-K05181463 SKB 10 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
99993 BRD-K05181463 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).