CMap Candidate Details

Structure:
CMap ID: C00405
Pert ID: BRD-A15931911
Compound Name: bucladesine
Targets: PRKACA
MoA: CAMP stimulant; Adenosine receptor agonist
SMILES: CCCC(=O)Nc1ncnc2n(cnc12)C1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1OC(=O)CCC
InchiKey: CJGYSWNGNKCJSB-ZBSNKJFMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4513 BRD-A15931911 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4837 BRD-A15931911 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.19
127761 BRD-A15931911 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127806 BRD-A15931911 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127835 BRD-A15931911 HA1E 0.04 uM 24 h -0.22 -0.92 0.07 0.24 0.86 0.15
127891 BRD-A15931911 HEK293 0.37 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.34
127965 BRD-A15931911 HUVEC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128015 BRD-A15931911 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128034 BRD-A15931911 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128095 BRD-A15931911 YAPC 0.37 uM 24 h 0.0 0.0 0.0 -0.18 -0.61 0.0
135591 BRD-A15931911 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135628 BRD-A15931911 HT29 0.01 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
135683 BRD-A15931911 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135730 BRD-A15931911 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).