CMap Candidate Details

Structure:
CMap ID: C00408
Pert ID: BRD-A16296925
Compound Name: indobufen
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor; Platelet aggregation inhibitor
SMILES: CCC(C(O)=O)c1ccc(cc1)N1Cc2ccccc2C1=O
InchiKey: AYDXAULLCROVIT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120271 BRD-A16296925 A549 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.47
120308 BRD-A16296925 HA1E 0.04 uM 24 h -0.22 -0.92 0.06 -0.3 -1.01 0.58
120400 BRD-A16296925 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120431 BRD-A16296925 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120465 BRD-A16296925 YAPC 0.125 uM 24 h -0.31 -1.28 0.76 0.0 0.0 0.0
128888 BRD-A16296925 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128923 BRD-A16296925 HELA 2.22 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
128942 BRD-A16296925 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).