CMap Candidate Details

Structure:
CMap ID: C04086
Pert ID: BRD-K05361803
Compound Name: SC-10
Targets: PRKCA
MoA: Protein kinase activator
SMILES: CCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12
InchiKey: MJMJERJFCHYXEM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2829 BRD-K05361803 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3132 BRD-K05361803 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.69 0.02
3592 BRD-K05361803 PC3 10 uM 6 h -0.26 -1.09 0.33 0.0 0.0 0.0
3937 BRD-K05361803 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44284 BRD-K05361803 A375 10 uM 6 h 0.0 0.0 0.0 0.3 1.05 0.57
44511 BRD-K05361803 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44826 BRD-K05361803 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45139 BRD-K05361803 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45407 BRD-K05361803 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45638 BRD-K05361803 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
45941 BRD-K05361803 NPC 10 uM 24 h -0.3 -1.24 0.64 -0.28 -0.96 0.43
46261 BRD-K05361803 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46577 BRD-K05361803 SKB 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
99994 BRD-K05361803 U2OS 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).