CMap Candidate Details

Structure:
CMap ID: C00409
Pert ID: BRD-A16311756
Compound Name: profenamine
Targets: CHRM1
MoA: Butyrylcholinesterase inhibitor; Cholinergic receptor antagonist
SMILES: CCN(CC)C(C)CN1c2ccccc2Sc2ccccc12
InchiKey: CDOZDBSBBXSXLB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6621 BRD-A16311756 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6917 BRD-A16311756 A549 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
7210 BRD-A16311756 HA1E 10 uM 24 h -0.2 -0.85 0.01 0.37 1.3 1.59
7511 BRD-A16311756 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7747 BRD-A16311756 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8294 BRD-A16311756 PC3 10 uM 24 h 0.24 0.99 0.09 -0.35 -1.16 1.11
8553 BRD-A16311756 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52018 BRD-A16311756 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).