CMap Candidate Details

Structure:
CMap ID: C00413
Pert ID: BRD-A16444946
Compound Name: acarbose
Targets: GAA; AMY2A; MGAM
MoA: Glucosidase inhibitor
SMILES: C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
InchiKey: XUFXOAAUWZOOIT-UGEKTDRHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24832 BRD-A16444946 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25062 BRD-A16444946 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.32 1.12 0.76
25467 BRD-A16444946 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44636 BRD-A16444946 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45070 BRD-A16444946 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.32
45869 BRD-A16444946 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
46181 BRD-A16444946 PHH 10 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
46498 BRD-A16444946 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96586 BRD-A16444946 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96656 BRD-A16444946 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).