CMap Candidate Details

Structure:
CMap ID: C04142
Pert ID: BRD-K05524748
Compound Name: dronedarone
Targets: --
MoA: --
SMILES: CCCCN(CCCC)CCCOc1ccc(cc1)C(=O)c1c(CCCC)oc2ccc(NS(C)(=O)=O)cc12
InchiKey: ZQTNQVWKHCQYLQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122538 BRD-K05524748 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122572 BRD-K05524748 A549 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.51
122595 BRD-K05524748 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122655 BRD-K05524748 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122675 BRD-K05524748 HT29 10 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
122710 BRD-K05524748 MCF10A 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
122747 BRD-K05524748 MCF??7.00 10 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
122766 BRD-K05524748 MDAMB231 10 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
122788 BRD-K05524748 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122810 BRD-K05524748 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130930 BRD-K05524748 HEK293 2.22 uM 24 h -0.22 -0.9 0.04 -0.34 -1.15 1.05
131032 BRD-K05524748 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.71
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).