CMap Candidate Details

Structure:
CMap ID: C04143
Pert ID: BRD-K05528470
Compound Name: L-745870
Targets: DRD4
MoA: Dopamine receptor antagonist
SMILES: Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1
InchiKey: OGJGQVFWEPNYSB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2980 BRD-K05528470 HA1E 10 uM 6 h 0.19 0.79 0.0 0.31 1.09 0.67
3133 BRD-K05528470 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.98
3462 BRD-K05528470 PC3 10 uM 24 h 0.29 1.2 0.43 -0.25 -0.83 0.16
3716 BRD-K05528470 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39087 BRD-K05528470 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39295 BRD-K05528470 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39621 BRD-K05528470 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39942 BRD-K05528470 HEPG2 10 uM 6 h 0.17 0.72 0.0 0.0 0.0 0.0
40222 BRD-K05528470 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.12 0.94
40451 BRD-K05528470 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40745 BRD-K05528470 NEU 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
41046 BRD-K05528470 NPC 10 uM 24 h 0.26 1.07 0.19 0.0 0.0 0.0
41373 BRD-K05528470 SKB 10 uM 24 h -0.24 -1.01 0.16 -0.18 -0.61 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).