CMap Candidate Details

Structure:
CMap ID: C04181
Pert ID: BRD-K05653692
Compound Name: DL-PDMP
Targets: ASAH1; UGCG
MoA: Glucosyltransferase inhibitor
SMILES: CCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2
InchiKey: UYNCFCUHRNOSCN-FYYLOGMGSA-N
Compound Aliases: dl-pdmp

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8901 BRD-K05653692 A375 60 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9083 BRD-K05653692 A549 60 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9346 BRD-K05653692 AGS 60 uM 6 h -0.32 -1.33 0.87 0.0 0.0 0.0
9652 BRD-K05653692 H1299 60 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.51
9876 BRD-K05653692 HA1E 60 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
10252 BRD-K05653692 HCC515 60 uM 6 h -0.21 -0.89 0.03 0.24 0.87 0.17
10449 BRD-K05653692 HCT116 60 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.13
10718 BRD-K05653692 HEPG2 60 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10934 BRD-K05653692 HT29 60 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.53
11131 BRD-K05653692 MCF??7.00 60 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11403 BRD-K05653692 NCIH2073 60 uM 6 h 0.0 0.0 0.0 0.38 1.35 1.72
11702 BRD-K05653692 NCIH508 60 uM 6 h 0.0 0.0 0.0 0.43 1.52 2.28
11973 BRD-K05653692 NCIH596 60 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12590 BRD-K05653692 PC3 60 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.21
12718 BRD-K05653692 SW480 60 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
12935 BRD-K05653692 THP1 60 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13198 BRD-K05653692 U937 60 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.15
13444 BRD-K05653692 VCAP 60 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99998 BRD-K05653692 U2OS 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).