CMap Candidate Details

Structure:
CMap ID: C04191
Pert ID: BRD-K05674516
Compound Name: PSI-7976
Targets: --
MoA: --
SMILES: CC(C)OC(=O)[C@H](C)N[P@@](=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@](C)(F)[C@@H]1O)Oc1ccccc1
InchiKey: TTZHDVOVKQGIBA-YBSJRAAASA-N
Compound Aliases: sofosbuvir

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122539 BRD-K05674516 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122573 BRD-K05674516 A549 1.11 uM 24 h -0.17 -0.7 0.0 -0.32 -1.09 0.83
122596 BRD-K05674516 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122628 BRD-K05674516 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122676 BRD-K05674516 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122711 BRD-K05674516 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122748 BRD-K05674516 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122767 BRD-K05674516 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122789 BRD-K05674516 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122811 BRD-K05674516 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130959 BRD-K05674516 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131033 BRD-K05674516 HUVEC 0.74 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).