CMap Candidate Details
Structure:
| CMap ID: | C00424 |
| Pert ID: | BRD-A16934955 |
| Compound Name: | nalbuphine |
| Targets: | OPRD1; OPRK1; OPRM1 |
| MoA: | Opioid receptor agonist; Opioid receptor antagonist |
| SMILES: | OC1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5OC1[C@]2(CCN3CC6CCC6)c54 |
| InchiKey: | NETZHAKZCGBWSS-OCKIPSRKSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24371 | BRD-A16934955 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24640 | BRD-A16934955 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24833 | BRD-A16934955 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.84 | 0.18 |
| 24982 | BRD-A16934955 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25124 | BRD-A16934955 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25468 | BRD-A16934955 | VCAP | 10 uM | 6 h | -0.19 | -0.77 | 0.0 | -0.24 | -0.79 | 0.11 |