CMap Candidate Details
Structure:
| CMap ID: | C00425 |
| Pert ID: | BRD-A16997652 |
| Compound Name: | protirelin |
| Targets: | TRHR |
| MoA: | Thyrotropin releasing hormone receptor agonist |
| SMILES: | NC(=O)C1CCCN1C(=O)C(Cc1c[nH]cn1)NC(=O)C1CCC(=O)N1 |
| InchiKey: | XNSAINXGIQZQOO-UHFFFAOYSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120245 | BRD-A16997652 | A375 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120282 | BRD-A16997652 | A549 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.43 | 1.53 | 2.3 |
| 120319 | BRD-A16997652 | HA1E | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120408 | BRD-A16997652 | MCF??7.00 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120440 | BRD-A16997652 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120478 | BRD-A16997652 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.3 | 1.57 |
| 128927 | BRD-A16997652 | HELA | 2.22 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128950 | BRD-A16997652 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.75 | 0.07 |