CMap Candidate Details

Structure:
CMap ID: C04261
Pert ID: BRD-K05901394
Compound Name: terguride
Targets: DRD2; HTR2A; HTR2B
MoA: Dopamine receptor agonist; Serotonin receptor antagonist
SMILES: CCN(CC)C(=O)N[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1
InchiKey: JOAHPSVPXZTVEP-QGPMSJSTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1534 BRD-K05901394 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1873 BRD-K05901394 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2261 BRD-K05901394 PC3 10 uM 24 h 0.3 1.23 0.5 0.41 1.44 2.21
2595 BRD-K05901394 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41902 BRD-K05901394 A549 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.46 15.35
42270 BRD-K05901394 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42606 BRD-K05901394 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42910 BRD-K05901394 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43283 BRD-K05901394 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43465 BRD-K05901394 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43772 BRD-K05901394 PHH 10 uM 24 h 0.28 1.17 0.36 0.0 0.0 0.0
44051 BRD-K05901394 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100000 BRD-K05901394 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.45
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).