CMap Candidate Details

Structure:
CMap ID: C04307
Pert ID: BRD-K06080977
Compound Name: eicosatetraynoic-acid
Targets: ALOX12; PPARA; PPARG; PTGS1
MoA: Cyclooxygenase inhibitor; Lipoxygenase inhibitor
SMILES: CCCCCC#CCC#CCC#CCC#CCCCC(=O)O
InchiKey: MGLDCXPLYOWQRP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33564 BRD-K06080977 A375 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.09
33770 BRD-K06080977 A549 10 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
34034 BRD-K06080977 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34306 BRD-K06080977 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.81
34548 BRD-K06080977 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34817 BRD-K06080977 HEPG2 10 uM 6 h 0.28 1.15 0.34 0.0 0.0 0.0
35084 BRD-K06080977 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35392 BRD-K06080977 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.33
36057 BRD-K06080977 PC3 10 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.24
36192 BRD-K06080977 PHH 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
36485 BRD-K06080977 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36767 BRD-K06080977 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98995 BRD-K06080977 NEU 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
99126 BRD-K06080977 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).