CMap Candidate Details

Structure:
CMap ID: C04352
Pert ID: BRD-K06198550
Compound Name: isorotenone
Targets: --
MoA: --
SMILES: COc1cc2OC[C@H]3Oc4c(ccc5oc(cc45)C(C)C)C(=O)[C@H]3c2cc1OC
InchiKey: DJDRQIXLFYUYAA-RTWAWAEBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2830 BRD-K06198550 HA1E 10 uM 24 h 0.22 0.93 0.05 0.29 1.02 0.49
3134 BRD-K06198550 HCC515 10 uM 24 h 0.25 1.04 0.15 -0.24 -0.79 0.11
3463 BRD-K06198550 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3718 BRD-K06198550 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44287 BRD-K06198550 A375 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.35 2.02
44513 BRD-K06198550 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44830 BRD-K06198550 ASC 10 uM 24 h 0.28 1.17 0.36 0.0 0.0 0.0
45142 BRD-K06198550 HEPG2 10 uM 6 h -0.24 -1.01 0.16 -0.42 -1.42 2.02
45410 BRD-K06198550 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45641 BRD-K06198550 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.28
45945 BRD-K06198550 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46265 BRD-K06198550 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46581 BRD-K06198550 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).