CMap Candidate Details

Structure:
CMap ID: C00436
Pert ID: BRD-A17448384
Compound Name: beclometasone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(Cl)C(O)CC2(C)C1(O)C(=O)CO
InchiKey: NBMKJKDGKREAPL-WOOYFSPWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21920 BRD-A17448384 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22193 BRD-A17448384 A549 10 uM 6 h 0.22 0.92 0.04 0.0 0.0 0.0
22370 BRD-A17448384 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22629 BRD-A17448384 HCC515 10 uM 6 h 0.21 0.89 0.02 0.0 0.0 0.0
22909 BRD-A17448384 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
23215 BRD-A17448384 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23499 BRD-A17448384 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
23780 BRD-A17448384 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24073 BRD-A17448384 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).